Antineoplastic drug NSC631570 modulates functions of hypoxic macrophages
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چکیده
منابع مشابه
Mathematical modelling of the use of macrophages as vehicles for drug delivery to hypoxic tumour sites.
Poor drug delivery and low rates of cell proliferation are two factors associated with hypoxia that diminish the efficacy of many chemotherapeutic drugs. Since macrophages are known to migrate specifically towards, and localize within, hypoxic tumour regions, a promising resolution to these problems involves genetically engineering macrophages to perform such anti-tumour functions as inducing c...
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Copyright: © 2016 Polo F, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. In the clinical practice, therapeutic drug monitoring (TDM) concerns the analytical determination of pharmaceutical drug concent...
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ژورنال
عنوان ژورنال: Cytology and Genetics
سال: 2013
ISSN: 0095-4527,1934-9440
DOI: 10.3103/s0095452713050095